The association between dietary quality and insomnia or sleep health among general population
Level of evidence: C
Higher adherence to Mediterranean and high-quality diets may decrease while higher intake of energy drinks may increase insomnia symptoms among general population.
Although most studies were of acceptable methodological quality, the overall certainty of evidence is low. The findings are based mainly on observational, cross-sectional studies with heterogeneity in design and outcome measures. The evidence is further limited by potential bias, confounding, imprecision, and reliance on self-reported data. Longitudinal and interventional studies are needed to confirm causality and clarify underlying mechanisms.
| Reference | Study type | Population | Intervention and comparison | Outcomes | Risk of bias [Table «Additional comments for included studies»2 Additional comments] |
|---|---|---|---|---|---|
| RCT=randomized controlled trial; SR=systematic review; MA=meta-analysis | |||||
| «Arab A, Lempesis IG, Garaulet M, et al. Sleep and the Mediterranean diet: A systematic review and meta-analysis. Sleep Med Rev 2025;80():102071 »1 | SR, MA | Children, adults general population | observational studies. | The association between sleep duration, sleep quality, and chronotype with the Mediterranean diet. Sleep duration and quality were assessed using the Pittsburgh sleep quality index (PSQI) and open questions. | Moderate |
| «Arab A, Karimi E, Garaulet M, et al. Dietary patterns and insomnia symptoms: A systematic review and meta-analysis. Sleep Med Rev 2024;75():101936 »2 | SR, MA | among the general population, China, Finland, France, Greece, Iran, Italy, Japan, Jordan, Korea, Mexico, Poland, Spain, Sweden, Turkey, the United States | observational studies | the association between dietary patterns and insomnia symptoms (as difficulty initiating sleep, maintaining sleep, and/or early morning awakening). | Moderate |
| «Pourmotabbed A, Awlqadr FH, Mehrabani S, et al. Ultra-Processed Food Intake and Risk of Insomnia: A Systematic Review and Meta-Analysis. Nutrients 2024;16(21): »3 | SR, MA | Adults, adolescents. France, Iran, Brazil, Mexico. | cross-sectional studies | The association between ultra-processed foods and the risk of insomnia | Moderate |
| «Shahdadian F, Boozari B, Saneei P. Association between short sleep duration and intake of sugar and sugar-sweetened beverages: A systematic review and meta-analysis of observational studies. Sleep Hea»4 | SR, MA | Children, adults | cross-sectional studies | the relation between short sleep duration and sugar and sugar-sweetened beverages intake | Moderate |
| «Nadeem IM, Shanmugaraj A, Sakha S, et al. Energy Drinks and Their Adverse Health Effects: A Systematic Review and Meta-analysis. Sports Health 2021;13(3):265-277 »5 | SR, MA | Children, adults. Asia, USA, Europe, Australia, Middle East | cross-sectional and RCT studies | To evaluate the adverse effects (i.e. insomnia) of energy drink consumption | Moderate |
| Reference | Comments |
|---|---|
| «Arab A, Lempesis IG, Garaulet M, et al. Sleep and the Mediterranean diet: A systematic review and meta-analysis. Sleep Med Rev 2025;80():102071 »1 | The nature of studies, variable quality of the data increase the risk of bias. |
| «Arab A, Karimi E, Garaulet M, et al. Dietary patterns and insomnia symptoms: A systematic review and meta-analysis. Sleep Med Rev 2024;75():101936 »2 | The nature of studies, variable quality of the data increase the risk of bias. Occurrence of insomnia syndrome was assessed by Insomnia severity index (ISI), Athens insomnia scale (AIS), Women's health initiative insomnia rating scale (WHIIRS), European organization for research and treatment of cancer quality of life questionnaire core 30 (EORTC QLQ-C30), Menopause rating scale (MRS), Jenkins sleep questionnaire (JSQ) and Duke structured interview for sleep disorders (DSISD). |
| «Pourmotabbed A, Awlqadr FH, Mehrabani S, et al. Ultra-Processed Food Intake and Risk of Insomnia: A Systematic Review and Meta-Analysis. Nutrients 2024;16(21): »3 | The nature of studies, variable UPF definition. |
| «Shahdadian F, Boozari B, Saneei P. Association between short sleep duration and intake of sugar and sugar-sweetened beverages: A systematic review and meta-analysis of observational studies. Sleep Hea»4 | The nature of studies, variable quality of the data increase the risk of bias. Short (vs. optimal) sleep duration in adults was associated with a 58% higher intake of energy drinks. Occurrence of insomnia syndrome was assessed by DSM-V and ICSD-3, ISI, Study questionnaire. |
| «Nadeem IM, Shanmugaraj A, Sakha S, et al. Energy Drinks and Their Adverse Health Effects: A Systematic Review and Meta-analysis. Sports Health 2021;13(3):265-277 »5 | The nature of studies. Assesment of the occurrence of insomnia syndrome was not reported. |
Results
| Reference | Number of studies and number of patients (I/C) | Absolute number of events (%) I | Absolute number of events (%) C | Relative effect (95% CI) |
|---|---|---|---|---|
| Level of evidence: very low * Statistically significant The quality of evidence is downgraded due to (study limitations, inconsistency, indirectness, imprecision, publication bias). The quality of evidence in upgraded due to large or very large effects, dose-response gradient, effect of plausible residual confounding). | ||||
| «Arab A, Karimi E, Garaulet M, et al. Dietary patterns and insomnia symptoms: A systematic review and meta-analysis. Sleep Med Rev 2024;75():101936 »2 | High-quality diet (highest vs. lowest adherence) 6 studies total 18988 | N/A | N/A | OR 0.66 * (0.48–0.90) [very low] |
| Mediterranean diet (highest vs. lowest adherence) 10 studies total 13511 | N/A | N/A | OR 0.86 * (0.79–0.93) [very low] | |
| DASH (highest vs. lowest adherence) 3 studies total 909 | N/A | N/A | OR 1.01 (0.94-1.07) [very low] | |
| «Pourmotabbed A, Awlqadr FH, Mehrabani S, et al. Ultra-Processed Food Intake and Risk of Insomnia: A Systematic Review and Meta-Analysis. Nutrients 2024;16(21): »3 | Ultraprocessed food consumption (higher vs. lower)
7 studies total 159427 | N/A | N/A | OR 1.53 * (1.20–1.95) [very low] |
| «Nadeem IM, Shanmugaraj A, Sakha S, et al. Energy Drinks and Their Adverse Health Effects: A Systematic Review and Meta-analysis. Sports Health 2021;13(3):265-277 »5 | Energy drinks 4 studies 63/63 | N/A | N/A | OR 5.02 * (95 % CI 1.72–14.63) [low] |
High-quality diet was estimated via the healthy eating index; highest vs. lowest adherence= Comparisons were made between people with the highest adherence to any specific dietary patterns and those with the lowest adherence; DASH=Dietary Approaches to Stop Hypertension diet is rich in fruits, vegetables, whole grains, lean proteins, and low-fat dairy, while limiting salt, saturated fats, sugar, and red meat. The Mediterranean diet is rich in vegetables, fruits, whole grains, legumes, nuts, fish, and olive oil. Ultraprocessed food defined as heavily industrially processed items containing artificial additives and high levels of sugar, fat, or salt with low nutritional fiber.
| Reference | Number of studies and number of patients (I/C) | Absolute number of events (%) I | Absolute number of events (%) C | Relative effect (95% CI) |
|---|---|---|---|---|
| Level of evidence: very low The quality of evidence is downgraded due to (study limitations, inconsistency, indirectness, imprecision, publication bias). The quality of evidence in upgraded due to large or very large effects, dose-response gradient, effect of plausible residual confounding) I= intervention; C=comparison; CI=confidence interval | ||||
| «Arab A, Lempesis IG, Garaulet M, et al. Sleep and the Mediterranean diet: A systematic review and meta-analysis. Sleep Med Rev 2025;80():102071 »1 | Mediterranea diet score (Insufficient vs. good -quality sleep) 13 studies overall 29 614 | N/A | N/A | OR 1.38 * (1.10–1.73) very low |
| Reference | Number of studies and number of patients (I/C) | Absolute number of events (%) I | Absolute number of events (%) C | Relative effect (95% CI) |
|---|---|---|---|---|
| Level of evidence: low The quality of evidence is downgraded due to (study limitations, inconsistency, indirectness, imprecision, publication bias). The quality of evidence in upgraded due to large or very large effects, dose-response gradient, effect of plausible residual confounding). I= intervention; C=comparison; CI=confidence interval | ||||
| «Arab A, Lempesis IG, Garaulet M, et al. Sleep and the Mediterranean diet: A systematic review and meta-analysis. Sleep Med Rev 2025;80():102071 »1 | Mediterranea diet score (insufficient vs. sufficient sleep duration) 13 studies total 227 151 | N/A | N/A | OR 1.39 * (1.04–1.85) low |
| «Shahdadian F, Boozari B, Saneei P. Association between short sleep duration and intake of sugar and sugar-sweetened beverages: A systematic review and meta-analysis of observational studies. Sleep Hea»4 | Soda intake (adults) (low vs. optimal sleep duration) 2 studies total 20566 | N/A | N/A | OR 1.20 * (1.12–1.28) moderate |
| Energy drinks intake (adults) (low vs. optimal sleep duration) 2 studies total 3641 | N/A | N/A | OR 1.58 * (1.31–1.90) low | |
References
- Arab A, Lempesis IG, Garaulet M, et al. Sleep and the Mediterranean diet: A systematic review and meta-analysis. Sleep Med Rev 2025;80():102071 «PMID: 40081182»PubMed
- Arab A, Karimi E, Garaulet M, et al. Dietary patterns and insomnia symptoms: A systematic review and meta-analysis. Sleep Med Rev 2024;75():101936 «PMID: 38714136»PubMed
- Pourmotabbed A, Awlqadr FH, Mehrabani S, et al. Ultra-Processed Food Intake and Risk of Insomnia: A Systematic Review and Meta-Analysis. Nutrients 2024;16(21): «PMID: 39519600»PubMed
- Shahdadian F, Boozari B, Saneei P. Association between short sleep duration and intake of sugar and sugar-sweetened beverages: A systematic review and meta-analysis of observational studies. Sleep Health 2023;9(2):159-176 «PMID: 36424247»PubMed
- Nadeem IM, Shanmugaraj A, Sakha S, et al. Energy Drinks and Their Adverse Health Effects: A Systematic Review and Meta-analysis. Sports Health 2021;13(3):265-277 «PMID: 33211984»PubMed
