Lisätietoa aiheesta

Additional comments for included studies

Lisätietoa aiheesta
7.5.2019
Current Care Guidelines working group Oral cancer

Taulukko 1. Additional comments for included studies
ReferenceComments
«Siddiqi K, Shah S, Abbas SM ym. Global burden of disease due to smokeless tobacco consumption in adults: analysis of data from 113 countries. BMC Med 2015;13:194 »1Swedish studies include 4, 6, 9, 10 In included studies exposure and comparison heterogenic, in some studies also unreliable and questionable eg. deceased cases and controls included [4], dose and duration of snuff use often lacking, comparisons made between snuff users and smokers instead of never users of any tobacco products.
«Asthana S, Labani S, Kailash U ym. Association of Smokeless Tobacco Use and Oral Cancer: A Systematic Global Review and Meta-Analysis. Nicotine Tob Res 2018;: »3European studies include 4, 6, 9
«Schildt EB, Eriksson M, Hardell L ym. Oral snuff, smoking habits and alcohol consumption in relation to oral cancer in a Swedish case-control study. Int J Cancer 1998;77:341-6 »4Exposure may be confounded: deceased cases and their deceased controls were included, (questionnaire filled by relatives).
Eligibility may be confounded: Only one female reported snuff use. Study design/outcome measures: Mortality was not analyzed although 235 cases were deceased
*Reporting: oral cancer risk ORs for snuff using ex-smokers and smokers are confusing compared to reported absolute numbers of cases
«Roosaar A, Johansson AL, Sandborgh-Englund G ym. Cancer and mortality among users and nonusers of snus. Int J Cancer 2008;123:168-73 »5Eligibility may be confounded: Only men included (no snuff using females in the cohort)
Exposure may be confounded: recorded only in the beginning
«Luo J, Ye W, Zendehdel K ym. Oral use of Swedish moist snuff (snus) and risk for cancer of the mouth, lung, and pancreas in male construction workers: a retrospective cohort study. Lancet 2007;369:201»6Eligibility may be confounded: females were excluded
Exposure may be confounded: recorded only in the beginning Selective reporting: big cohort, mortality not analyzed
«Timberlake DS, Nikitin D, Johnson NJ ym. A longitudinal study of smokeless tobacco use and mortality in the United States. Int J Cancer 2017;141:264-270 »7Exposure may be confounded: recorded only in the beginning
Control of confounding factors: not adjusted to alcohol use (not recorded) Median follow up-time quite short (8,8 years) for all-cause mortality
«Hansson J, Galanti MR, Hergens MP ym. Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival. J Intern Med 2014;276:87-95 »8Exposure may be confounded: recorded only in the beginning,
Eligibility confounded: only men included
Reporting: current snuff users compared to noncurrent use (not to never use)
«Sinha DN, Suliankatchi RA, Gupta PC ym. Global burden of all-cause and cause-specific mortality due to smokeless tobacco use: systematic review and meta-analysis. Tob Control 2018;27:35-42 »9Significant heterogeneity between studies I2= 92,7
All included studies had moderate risk for exposure bias, 9/16 studies moderate risk for confounding factors

Kirjallisuutta

  1. Siddiqi K, Shah S, Abbas SM ym. Global burden of disease due to smokeless tobacco consumption in adults: analysis of data from 113 countries. BMC Med 2015;13:194 «PMID: 26278072»PubMed
  2. Wyss AB, Hashibe M, Lee YA ym. Smokeless Tobacco Use and the Risk of Head and Neck Cancer: Pooled Analysis of US Studies in the INHANCE Consortium. Am J Epidemiol 2016;184:703-716 «PMID: 27744388»PubMed
  3. Asthana S, Labani S, Kailash U ym. Association of Smokeless Tobacco Use and Oral Cancer: A Systematic Global Review and Meta-Analysis. Nicotine Tob Res 2018;: «PMID: 29790998»PubMed
  4. Schildt EB, Eriksson M, Hardell L ym. Oral snuff, smoking habits and alcohol consumption in relation to oral cancer in a Swedish case-control study. Int J Cancer 1998;77:341-6 «PMID: 9663593»PubMed
  5. Roosaar A, Johansson AL, Sandborgh-Englund G ym. Cancer and mortality among users and nonusers of snus. Int J Cancer 2008;123:168-73 «PMID: 18412245»PubMed
  6. Luo J, Ye W, Zendehdel K ym. Oral use of Swedish moist snuff (snus) and risk for cancer of the mouth, lung, and pancreas in male construction workers: a retrospective cohort study. Lancet 2007;369:2015-2020 «PMID: 17498797»PubMed
  7. Timberlake DS, Nikitin D, Johnson NJ ym. A longitudinal study of smokeless tobacco use and mortality in the United States. Int J Cancer 2017;141:264-270 «PMID: 28411395»PubMed
  8. Hansson J, Galanti MR, Hergens MP ym. Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival. J Intern Med 2014;276:87-95 «PMID: 24548296»PubMed
  9. Sinha DN, Suliankatchi RA, Gupta PC ym. Global burden of all-cause and cause-specific mortality due to smokeless tobacco use: systematic review and meta-analysis. Tob Control 2018;27:35-42 «PMID: 27903956»PubMed
  10. Rosenquist K, Wennerberg J, Schildt EB ym. Use of Swedish moist snuff, smoking and alcohol consumption in the aetiology of oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern Sweden. Acta Otolaryngol 2005;125:991-8 «PMID: 16193590»PubMed
  11. Lewin F, Norell SE, Johansson H ym. Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden. Cancer 1998;82:1367-75 «PMID: 9529030»PubMed