Selaa tietokantoja

Lääkärin käsikirja 1179

Käypä hoito 197

Laskurit ja lomakkeet 74

Kuvat, äänet ja videot 2473

Tietoa potilaalle 1973

Hoito- ja palveluketjut 459

Cochrane Reviews 9159

Kiireettömän hoidon perusteet 25

Laboratoriotutkimukset 6816

Duodecim-lehti 21431

Lääkärilehti 19004

Yleislääkäri-lehti 125

Sydänääni-lehti 94

Matkailijan terveysopas 345

Potilasohjaus 19

Palveluvalikoimaneuvosto 203

Hoitosuositukset ja hoito-ohjeet 33

Toimintakyky ja kuntoutus 107

Harvinaiset sairaudet 355

Puolustusvoimat 41

Näytönastekatsaukset 3033

Näytönastekatsaukset 46

Evidence summaries 2476

Interventions for hand eczema

Addiction medicine 61

Administration 20

Adolescent psychiatry 22

Alcohol-related diseases 17

Anaesthesiology 64

Child neurology 14

Child psychiatry 35

Clinical chemistry 1

Clinical neurophysiology 4

Clinical pharmacology 180

Clinical physiology 2

Dermatology 127

Emergency medicine 10

Endocrinology 133

Forensic medicine 1

Gastroenterology 161

General practice 10

Gynaecology 235

Health informatics 2

Infectious diseases 338

Infectious diseases and vaccinations 1

Internal medicine 409

Acetylcholinesterase inhibitor treatment for myasthenia gravis

Acupuncture for acute stroke

Acupuncture for Bell's palsy

Acupuncture for migraine prophylaxis

Acupuncture for tension-type headache

Adjuvant treatment of anaplastic oligodendrogliomas and oligoastrocytomas

Adjuvant treatment to levodopa therapy in Parkinson´s disease patients with motor complications

Alcohol as a risk factor in cerebral haemorrhage

Alcohol as the cause of epileptic seizures

Alemtuzumab for multiple sclerosis

Amantadine for fatigue in multiple sclerosis

Amitriptyline for postherpetic neuralgia (PHN) in adults

Anthelmintics for neurocysticercosis

Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures

Antibiotic therapy for preventing infections in patients with acute stroke

Antibiotics for syphilis during pregnancy

Anticholinergic burden (prognostic factor) for prediction of cognitive decline in older adults with no known cognitive syndrome

Anticoagulant treatment in acute cardioembolic stroke

Anticoagulants for acute ischaemic stroke

Anticoagulation for cerebral sinus thrombosis

Anticonvulsants for diabetic neuropathy

Anticonvulsants for tinnitus

Antidepressant drugs for narcolepsy

Antidepressants for depression in dementia

Antidepressants for depression in Parkinson's disease

Antidepressants for neuropathic pain

Antidepressants for people with epilepsy and depression

Antiepileptic drugs for preventing seizures in people with brain tumours

Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage

Antioxidant treatment for amyotrophic lateral sclerosis

Antiplatelet therapy for acute ischaemic stroke

Antiplatelet therapy for aneurysmal subarachnoid haemorrhage

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia

Anti-spasticity agents for multiple sclerosis

Antithrombotic drugs for carotid dissection

Antithrombotic treatment after stroke due to intracerebral haemorrhage

Antivirals for Bell's palsy (idiopathic facial paralysis)

Antivirals for postherpetic neuralgia

Ascorbic acid for the treatment of Charcot-Marie-Tooth disease

Aspirin for acute treatment of episodic tension-type headache in adults

Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease

Aspirin with or without antiemetic for acute migraine headaches in adults

Atenolol for preventing stroke recurrence

Atypical antipsychotics for aggression and psychosis in Alzheimer's disease

Azathioprine for multiple sclerosis

Azathioprine, interferon beta-1a or methotrexate for chronic inflammatory demyelinating polyradiculoneuropathy

Behavioural and cognitive-behavioural interventions for outwardly-directed aggressive behaviour in people with intellectual disabilities

Beta-blockers for essential tremor

Betahistine for Ménière's disease and vertigo

Biofeedback for tension-type headache

Blood pressure alteration in acute stroke

Blood pressure lowering for prevention of dementia in patients without prior cerebrovascular disease

Blood pressure reduction soon after acute ischaemic stroke

Botulinum toxin type A for blepharospasm

Botulinum toxin type A therapy for hemifacial spasm

Botulinum toxins A and B for cervical dystonia

Botulinum toxins for the prevention of migraine in adults

Brivaracetam add‐on therapy for drug‐resistant epilepsy

Bromocriptine versus levodopa in early Parkinson's disease

Bromocriptine/levodopa combined vs. levodopa alone for early Parkinson's disease

Cabergoline for levodopa-induced complications in Parkinson's disease

Cabergoline versus bromocriptine for levodopa-induced complications in Parkinson's disease

Calcium antagonists as an add-on therapy for drug-resistant epilepsy

Calcium antagonists for stroke

Carbamazepine for acute and chronic pain

Carbamazepine versus phenytoin monotherapy for epilepsy

Care delivery and self-management strategies for adults with epilepsy

Carotid endarterectomy for asymptomatic carotid stenosis

Carotid endarterectomy for symptomatic carotid stenosis

Cholinesterase inhibitors for Alzheimer’s disease

Cholinesterase inhibitors for Lewy body dementia

Cholinesterase inhibitors for mild cognitive impairment

Cholinesterase inhibitors for Parkinson's disease dementia

Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis/motor neuron disease

Circuit class therapy for improving mobility after stroke

Clobazam as add-on for refractory epilepsy

Clobazam monotherapy for partial-onset or generalized-onset seizures

Closure vs. medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or TIA

Cognitive behavioural therapy for tinnitus

Cognitive rehabilitation for attention deficits following stroke

Cognitive rehabilitation for memory deficits after stroke

Cognitive rehabilitation for spatial neglect following stroke

Colony stimulating factors including erythropoietin (EPO), granulocyte colony stimulating factor (G-CSF) and analogues for stroke

Combination therapy with cholinesterase inhibitors and memantine for Alzheimer’s disease

Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death

Constraint-induced movement therapy for upper extremities in stroke patients

Continuous vs. intermittent physiological monitoring for acute stroke

Cooling therapy for acute stroke

Corticosteroid treatment for idiopathic facial paralysis (Bell's palsy)

Corticosteroids for acute ischaemic stroke

Corticosteroids for acute optic neuritis

Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy

Corticosteroids for Guillain-Barré syndrome

Corticosteroids for managing tuberculous meningitis

Corticosteroids for myasthenia gravis

Corticosteroids for preventing postherpetic neuralgia

Corticosteroids for subarachnoid or intracerebral haemorrhage

Corticosteroids for the long-term treatment in multiple sclerosis

Corticosteroids for the treatment of Duchenne muscular dystrophy

Corticosteroids for the treatment of vestibular neuritis

Corticosteroids or ACTH for acute exacerbations in multiple sclerosis

Creatine for amyotrophic lateral sclerosis

Creatine for treating muscle disorders

CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)

Cyclophosphamide for multiple sclerosis

Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in SLE

Dabigatran versus vitamin K antagonists in non-valvular atrial fibrillation

Deep brain and cortical stimulation for epilepsy

Deep brain stimulation for Parkinson disease

Dexamethasone for acute bacterial meningitis in children

Diagnosis of syncope

Diclofenac for acute migraine

Dietary supplement (Souvenaid®) for Alzheimer's disease

Dimethyl fumarate for multiple sclerosis

Direct oral anticoagulants versus warfarin among atrial fibrillation patients with chronic kidney disease

Does this patient with headache need neuroimaging?

Donepezil for Alzheimer’s disease

Donepezil for vascular cognitive impairment

Dopamine agonist therapy in early Parkinson's disease

Dose-response effect of aspirin on stroke

Drug management for acute tonic-clonic convulsions in children

Drug therapy for preventing post-dural puncture headache

Drug therapy for treating post-dural puncture headache

Drug treatment for myotonia

Early supported discharge services for people with acute stroke

Early versus late antiepileptic drug withdrawal in pediatric epilepsy

Effect of the treatment of type 2 diabetes mellitus on the development of cognitive impairment and dementia

Effects of electromechanical and robot-assisted therapy on upper limb recovery after stroke

Electrical stimulation and mental practice for function of the upper limb after stroke

Electromechanical-assisted training for walking after stroke

Electromyographic biofeedback for the recovery of motor function after stroke

Electrostimulation for promoting recovery of movement or functional ability after stroke

Enteral tube feeding for amyotrophic lateral sclerosis/motor neuron disease

Epidural blood patching for post-dural puncture headache

Epley manouvere for benign paroxysmal positional vertigo

Eslicarbazepine add-on for drug-resistant partial epilepsy

Exercise programs for people with dementia

Exercise therapy for multiple sclerosis

Extracranial-intracranial arterial bypass surgery for occlusive carotid artery disease

Factor Xa inhibitors versus vitamin K antagonists for preventing embolism in patients with atrial fibrillation

Felbamate as an add-on therapy for refractory epilepsy

Fibrinogen-depleting agents for acute ischaemic stroke

Fingolimod for relapsing-remitting multiple sclerosis

Fitness training for cardiorespiratory conditioning after traumatic brain injury

Folic acid with or without vitamin B12 for cognition and dementia

Gabapentin for chronic neuropathic pain in adults

Gabapentin for drug resistant partial epilepsy

Gabapentin for fibromyalgia

Galantamine for Alzheimer’s disease

Galantamine for vascular cognitive impairment

Gamma aminobutyric acid (GABA) receptor agonists for acute stroke

Gamma-aminobutyric-acid (GABA) agonists for antipsychotic-induced tardive dyskinesia (TD)

Glatiramer acetate for multiple sclerosis

Haemostatic therapies for acute spontaneous intracerebral haemorrhage

Haloperidol for agitation in dementia

Hemiarginate in acute porphyria

High-dose B vitamins in Alzheimer’s disease

Homocysteine lowering interventions for preventing cardiovascular events

Hormone replacement therapy to maintain cognitive function in women with dementia

Ibuprofen for acute migraine

Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure

Immunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis (RRMS): a network meta-analysis

Immunosuppressive agents for myasthenia gravis

Immunosuppressive treatment for multifocal motor neuropathy

Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting

Information provision for stroke patients and their caregivers

Interferon beta for secondary progressive multiple sclerosis

Interferon in relapsing-remitting multiple sclerosis

Interventions for fatigue in Parkinson's disease

Interventions for increasing ankle range of motion in patients with neuromuscular disease

Interventions for motor apraxia following stroke

Interventions for nutritional support in subacute stroke

Interventions for preventing depression after stroke

Interventions for preventing falls after stroke

Interventions for visual field defects in patients with stroke

Interventions in the management of serum lipids for preventing stroke recurrence

Intranasal sumatriptan for acute migraine

Intravenous immunoglobulin for dermatomyositis

Intravenous immunoglobulin for exacerbations of myasthenia gravis

Intravenous immunoglobulin for Guillain-Barré syndrome

Intravenous immunoglobulin for multifocal motor neuropathy

Intravenous immunoglobulin (IVIg) for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

Intravenous thrombolysis in stroke patients over 80 years versus under 80 years of age

Iron for restless legs syndrome

Ischaemic stroke and myocardial infarction risk with combined oral contraceptives

Ketogenic diets for epilepsy in children

Ketoprofen for episodic tension-type headache in adults

Laboratory diagnosis of Lyme disease

Lacosamide add-on therapy for partial epilepsy

Lamotrigine add-on for drug-resistant partial epilepsy

Lamotrigine for acute and chronic pain

Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review

Levetiracetam for partial epilepsy in adults

Levodopa for restless legs

Local anesthetic sympathetic blockade for complex regional pain syndrome

Low-molecular-weight heparins vs. standard heparin for acute ischaemic stroke

Magnesium for skeletal muscle cramps

Magnesium sulphate for women at risk of preterm birth for neuroprotection of the foetus

Magnetic resonance imaging for the early diagnosis of multiple sclerosis

Management of faecal incontinence and constipation in adults with central neurological diseases

Mannitol for acute stroke

Massage and touch for dementia

Mechanical ventilation for amyotrophic lateral sclerosis

Melatonin for cognitive impairment

Melatonin for preventing and treating jet lag

Melatonin for sleep disorders

Memantine for Alzheimer’s disease

Memantine for vascular dementia

Memory rehabilitation in multiple sclerosis

Metal protein attenuating compounds for Alzheimer's disease

Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI)

Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations

Mitoxantrone for multiple sclerosis

Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease

Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child

Montreal Cognitive Assessment for the diagnosis of Alzheimer’s disease and other dementias

Multi-disciplinary rehabilitation for acquired brain injury in adults of working age

Multidisciplinary rehabilitation for adults with multiple sclerosis

Music-based therapeutic interventions for people with dementia

Naftidrofuryl for acute stroke

Naproxen for acute migraine headaches in adults

Natalizumab for relapsing remitting multiple sclerosis

Needle gauge and tip designs for preventing post-dural puncture headache

Neuropsychological rehabilitation for multiple sclerosis

Nimodipine for dementia

Nocturnal mechanical ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders

Non-drug therapies for lower limb muscle cramps

Non-pharmacological interventions for perceptual disorders following stroke and other adult-acquired, non-progressive brain injury

Non-pharmacological interventions for spasticity in multiple sclerosis

Normobaric and hyperbaric oxygen therapy for the treatment and prevention of migraine and cluster headache

Nortriptyline and gabapentin, alone and in combination for neuropathic pain

Occupational therapy after stroke

Occupational therapy for patients with Parkinson's disease

Omega-3 fatty acid for the treatment and prevention of Alzheimer's disease

Opioid switching to improve pain relief and drug tolerability

Opioids for neuropathic pain

Opioids for restless legs syndrome

Oral sumatriptan for acute migraine

Oral versus intravenous steroids for treatment of relapses in multiple sclerosis

Organised inpatient (stroke unit) care for stroke

Orthotic devices after stroke and other non-progressive brain lesions

Overground physical therapy gait training for chronic stroke patients with mobility deficits

Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures

Oxcarbazepine versus phenytoin monotherapy for epilepsy

Oxycodone for neuropathic pain in adults

Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults

Paracetamol with or without an antiemetic for acute migraine

Partial seizure onset in alcoholics

Patch angioplasty versus primary closure for carotid endarterectomy

Percutaneous vascular interventions for acute ischaemic stroke

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack

Personal assistance for adults (19-64) with both physical and intellectual impairments

Pharmaceutical interventions for emotionalism after stroke

Pharmacologic treatment for memory disorder in multiple sclerosis

Pharmacological interventions for epilepsy in people with intellectual disabilities

Pharmacological treatments for preventing epilepsy following traumatic head injury

Pharmacotherapies for sleep disturbances in dementia

Phenobarbitone vs. phenytoin for partial onset seizures and generalized onset tonic-clonic seizures

Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures

Physical fitness training for stroke patients

Physical methods for preventing deep vein thrombosis in stroke

Physical therapy after stroke

Physical therapy for Bell’s palsy (idiopathic facial paralysis)

Physiotherapy for patients with Parkinson's disease

Physiotherapy for the recovery of postural control and lower limb function following stroke

Piracetam for acute stroke

Piracetam for dementia or cognitive impairment

Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy

Plasma exchange for Guillain-Barré syndrome

Plasma exchange for myasthenia gravis

Polyunsaturated fatty acid supplementation for drug-resistant epilepsy

Polyunsaturated fatty acids for multiple sclerosis

Posture and fluids for preventing post-dural puncture headache

Pregabalin add-on for drug-resistant partial epilepsy

Pregabalin monotherapy for epilepsy

Pre-hospital antibiotics for meningococcal disease

Prevention of dementia by statins

Preventive treatments for recurrences of febrile seizures

Psychological interventions for multiple sclerosis

Psychosocial interventions for chronic orofacial pain

Psychostimulants for hypersomnia in myotonic dystrophy

Quinine for muscle cramps

Recombinant human insulin-like growth factor I for amyotrophic lateral sclerosis/motor neuron disease

Recombinant interferon beta for delaying conversion of the first demyelinating event to multiple sclerosis

Rectal sumatriptan for acute migraine

Reducing falls in acute hospitals

Rehabilitation for foot drop in neuromuscular disease

Rehabilitation for patients living at home more than one year after stroke

Rehabilitation for stroke patients at home

Repetitive task training for improving functional ability after stroke

Riluzole for patients with ALS

Risk of ischaemic stroke in people with migraine with aura

Risk of ischaemic stroke in persons with migraine without aura using combined hormonal contraception

Rivastigmine for Alzheimer’s disease

Rivastigmine for vascular cognitive impairment

Rufinamide add‐on therapy for refractory epilepsy

Sartans in migraine prophylaxis

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery

Selegeline for early Parkinson's disease

Signs, symptoms, and simple tests in the diagnosis of myasthenia gravis

Simultaneous bilateral training for improving arm function after stroke

Smoking and dementia

Sonothrombolysis for acute ischaemic stroke

Speech and language therapy for aphasia following stroke

Speech and language therapy for dysarthria in Parkinson's disease

SSRIs and SNRIs for preventing tension-type headaches and migraine

Statins for multiple sclerosis

Statins for the treatment of Alzheimer's disease

Strategies for improving adherence to antiepileptic drug treatment in epilepsy

Subcutaneous sumatriptan in migraine

Sumatriptan plus naproxen for acute migraine attacks in adults

Surgery for epilepsy

Surgery for primary supratentorial intracerebral haemorrhage

Surgical decompression for cerebral oedema in acute ischaemic stroke

Surgical management of ulnar nerve compression at the elbow

Surgical modalities for trigeminal neuralgia

Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease

Symptoms in the diagnosis of stroke

Temozolomide for high grade glioma

Teriflunomide for multiple sclerosis

The efficacy of SSRIs in the management of chronic pain

The prognostic value of glucose levels in acute stroke

Therapeutic exercise for amyotrophic lateral sclerosis (ALS)

Therapeutic interventions for disease progression in Huntington's disease

Therapeutic interventions for symptomatic treatment in Huntington's disease

Therapeutic monitoring of antiepileptic drugs for epilepsy

Thiamine for Wernicke-Korsakoff syndrome in alcohol abuse

Thienopyridine derivatives (ticlopidine, clopidogrel) versus aspirin or aspirin-dipyridamole for preventing serious vascular events in high risk patients

Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke

Thrombolysis for acute ischaemic stroke

Tiagabine add-on for drug-resistant partial epilepsy

Topical high concentration capsaicin for chronic neuropathic pain in adults

Topiramate add-on for drug-resistant partial epilepsy

Topiramate for essential tremor

Topiramate for the prophylaxis of episodic migraine in adults

Topiramate versus carbamazepine monotherapy for epilepsy

Training for muscle diseases

Tramadol for neuropathic pain

Transcranial magnetic stimulation for the treatment of epilepsy

Transcranial stimulation therapies for improving function after stroke

Transcutaneous electrical nerve stimulation (TENS) for chronic pain

Transdermal and oral hormone replacement therapy and the risk of stroke

Treadmill training and body weight support for walking after stroke

Treadmill training for patients with Parkinson's disease

Treating dopamimetic psychosis in Parkinson's disease

Treatment for ataxia in multiple sclerosis

Treatment for cramps in amyotrophic lateral sclerosis

Treatment for epilepsy in pregnancy

Treatment for familial amyotrophic lateral sclerosis

Treatment for Lambert-Eaton myasthenic syndrome

Treatment for periodic paralysis

Treatment for postpolio syndrome

Treatment for spasticity in amyotrophic lateral sclerosis/motor neuron disease

Treatment of dysphagia in long-term, chronic muscle disease

Treatment of early Lyme disease

Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews

Triptans for acute cluster headache

Triptans for migraine

Vaccines for preventing tick-borne encephalitis

Valproate for agitation in dementia

Valproate for the prophylaxis of episodic migraine in adults

Vasoactive drugs for acute ischaemic stroke

Water-based exercises for improving activities of daily living after stroke

Venlafaxine in the treatment of neuropathic pain

Very early versus conventional mobilisation after stroke

Virtual reality for stroke rehabilitation

Vitamin E for Alzheimer's dementia and mild cognitive impairment

Vitamin K antagonists versus antiplatelet therapy after TIA or minor ischaemic stroke of presumed arterial origin

Vitamins for epilepsy

Zolmitriptan for acute migraine

Zonisamide add-on for drug-resistant partial epilepsy

Neurosurgery 18

Nutritional medicine 49

Occupational health 13

Occupational health service 2

Ophthalmology 42

Orthopaedics 103

Otorhinolaryngology 106

Paediatric surgery 5

Paediatrics 162

Physical and rehabilitation medicine 147

Plastic surgery 8

Public health 16

Pulmonary diseases 148

Radiation therapy 5

Resource-poor settings 47

Rheumatology 74

School health service 3

Sexually transmitted diseases 32

Sports medicine 26

Substance-related disorders 1

Thoracic surgery 9

Traffic medicine 5

Traumatology 28

Vascular surgery 49